sodium tetradecyl sulfate indications

Sodium tetradecyl sulfate injection is for intravenous use only. The strength of solution required depends on the size and degree of varicosity. In general, the 1% solution will be found most useful with the 3% solution preferred for larger varicosities. The dosage should be kept small, using 0.5 mL to 2 mL (preferably 1 mL maximum) for each ...

Generally use 1% solution; 3% solution preferred for larger varicosities. 5–20 mg of the 1% sodium tetradecyl sulfate solution (0.5–2 mL, preferably ≤2) or 15–60 mg of the 3% sodium tetradecyl sulfate solution (0.5–2 mL, preferably ≤2) recommended by manufacturer for each injection site. Do not exceed 2 mL per injection site or 10 ...

Medscape - Indication-specific dosing for Sotradecol, Trombovar (sodium tetradecyl sulfate), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. News …

Sodium tetradecyl sulfate; Adult Indications & Dosage: Pediatric Indications & Dosage: Contraindications: Warnings & Precautions: Adverse Reactions: Drug Interactions: ... Sodium tetradecyl sulfate is a sclerosing Agent that is FDA approved for the treatment of small uncomplicated varicose veins of the lower extremities.

Sodium tetradecyl sulfate is a medication used to treat small uncomplicated varicose veins in the lower limbs. Varicose veins are superficial, twisted, enlarged veins that appear just below the skin surface, and cause pain and discomfort. Sodium tetradecyl sulfate is injected into different sites along the swollen vein, which blocks blood flow into …

Sodium Tetradecyl Sulfate 4/5. Consumer Information Use and Disclaimer This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential

Sodium tetradecyl sulfate should only be administered by a physician familiar with the diagnosis and treatment of conditions affecting the venous system and with the proper injection technique. Extravasation may result in severe local adverse reactions including necrosis. Extreme care in needle placement and use of the minimal effective …

Abstract. Background: Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have …

8600 Rockville Pike. HHS Vulnerability Disclosure. No information is available on the clinical use of sodium tetradecyl sulfate during breastfeeding. Although sodium tetradecyl sulfate is unlikely to adversely affect the breastfed infant, international guidelines recommend that breastfeeding be withheld for 2 days after sclerotherapy. [1]

It is also commonly used as an adjunctive treatment for tributaries of the saphenous vein after saphenous obliteration by endovenous laser, radiofrequency, or …

Sotradecol (sodium tetradecyl sulfate injection) is a sterile nonpyrogenic solution for intravenous use as a sclerosing agent. 1% 20 mg/2 mL (10 mg/mL): Each mL contains sodium tetradecyl sulfate 10 mg, benzyl alcohol 0.02 mL and dibasic sodium phosphate, anhydrous 4.0 mg in Water for Injection. pH 7.9; monobasic sodium phosphate and/or …

In the rat, the acute intravenous LD 50 of sodium tetradecyl sulfate was estimated to be between 72 mg/kg and 108 mg/kg. Purified sodium tetradecyl sulfate was found to have an LD 50 of 2 g/kg when administered orally by stomach tube as a 25% aqueous solution to rats. In rats given 0.15 g/kg in drinking water for 30 days, no …

It is a sterile aqueous injection of Sodium Tetradecyl Sulfate (STS), an anionic detergent. It has been used in the treatment of varicose veins since 1946. Fibrovein is manufactured under cGMP conditions and complies with all EU regulations. The product was first registered in the UK in 1967 when it was marketed under the name of STD injection.

Each milliliter of 3 % STS contains 30 mg of sodium tetradecyl sulfate, 0.02 ml of benzyl alcohol, and 9.0 mg of dibasic sodium phosphate, anhydrous in water for injection at a pH of 7.9; monobasic sodium phosphate and/or sodium hydroxide were added, if needed for pH adjustment . All the patients received an oral analgesic and a …

Sotradecol® (sodium tetradecyl) (sodium tetradecyl sulfate injection) is indicated in the treatment of small uncomplicated varicose veins of the lower …

Indication. For the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves. Build, train, …

Sodium tetradecyl sulfate is a sclerosing (skler-OH-sing) agent. It works by increasing the formation of blood clots and scar tissue inside certain types of veins. This helps decrease dilation of enlarged veins. Sodium tetradecyl sulfate is used to treat small uncomplicated varicose veinsin the …

Sodium tetradecyl sulfate (STS) is an anionic surfactant used in the sclerosant drug Sotradecol. It is commonly used in the treatment of varicose and spider veins of the leg, during the procedure of sclerotherapy. ... Indication : Varicose veins; Treatment of upper GI bleeding due to esophageal varices. Contraindications : Hypersensitivity ...

4.1 Therapeutic indications Fibrovein 3% and 1%: For the treatment of varicose veins of the leg by injection sclerotherapy. Fibrovein 0.5%: For the treatment of varicose veins and venous flares of the leg by injection ... • Hypersensitivity to sodium tetradecyl sulphate or to any component of the preparation and allergic conditions.

Sodium tetradecyl sulfate, a synthetic surfactant (soap), is an FDA-approved sclerosant. It is commercially available in 1% or 3% standard concentrations. This sclerosant is reliable, safe, and effective. ... The elements of the consent should include the indications for sclerotherapy, available alternative treatments, potential complications ...

Pharmacodynamics. Sodium tetradecyl sulfate is an anionic surfactant which occurs as a white, waxy solid. It is used as a sclerosing agent in sclerotherapy. Sclerotherapy is an injection of a sclerosing agent directly through the skin into a lesion and is used primarily for slow-flow vascular anomalies, particularly for venous malformation …

PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice

Sodium tetradecyl sulfate is 7-ethyl-2-methyl-4-hendec-anol sodium sulfate (C14H29NaSO4). It is a synthetic an-ionic surfactant that is available as 1% and 3% aqueous solutions with 2% benzyl alcohol and is buffered to a pH of 7.9 with sodium phosphate.1,4It is packaged in 2-mL. TABLE 1. Sclerosants. Volume, mL.

Sodium tetradecyl sulfate is a sclerosing (skler-OH-sing) agent. It works by increasing the formation of blood clots and scar tissue inside certain types of veins. This helps decrease dilation of enlarged veins. Sodium tetradecyl sulfate is used to treat small uncomplicated varicose veins in the legs.

Sodium tetradecyl sulfate, a drug approved by the FDA for the treatment of varicose veins of lower extremities, makes the submucosal tissue fibrotic, and then fixes the hemorrhoidal tissue. The common method of sclerotherapy is to inject 0.5–2.0 mL of 1% sodium tetradecyl sulfate or 5% phenol under the mucosa at the top of the …

INDICATIONS AND USAGE. Sotradecol (sodium tetradecyl sulfate injection) is indicated in the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves. ... Purified sodium tetradecyl sulfate was found to have an LD 50 of 2 g/kg when administered orally by stomach tube as a 25% ...

Sodium tetradecyl sulfate is a medication used to treat small uncomplicated varicose veins in the lower limbs. Varicose veins are superficial, twisted, enlarged veins …

SODIUM TETRADECYL SULFATE (SOE dee um tet ra DES uhl SUHL feyt) is used to improve the appearance of varicose veins. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME (S): Sotradecol. Cleveland Clinic is a non-profit academic medical center.

TROMBOVAR® Therapex Sodium Tetradecyl Sulfate Sclerosing Agent. Indications And Clinical Uses: Sclerosing treatment of varicose veins in the legs, using compression sclerotherapy. Contra-Indications: Incompetency of collateral deep veins in the legs; incompetency of the valves of the greater and lesser saphenous veins before ligation of …

Sodium tetradecyl sulfate is 7-ethyl-2-methyl-4-hendecanol sodium sulfate (C 14 H 29 NaSO 4). It is a synthetic anionic surfactant that is available as 1% and 3% aqueous solutions with 2% benzyl alcohol and is buffered to a pH of 7.9 with sodium phosphate.

A Prospective Clinical Trial Evaluating the Efficacy of 1.5% Sodium Tetradecyl Sulfate Injection for the Treatment of Epidermoid Cysts The objective of this study is to determine the efficacy, safety, tolerability, and patient satisfaction associated with the treatment of epidermoid cysts with injected 1.5% sodium tetradecyl sulfate …

Sodium tetradecyl sulfate is an anionic surfactant which occurs as a white, waxy solid. The structural formula is as follows: C 14 H 29 NaSO 4 7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt MW 316.44. Sodium tetradecyl sulfate injection is a sterile nonpyrogenic solution for intravenous use as a sclerosing agent.

Descriptions. Sodium tetradecyl sulfate injection is used to treat small varicose veins of the lower legs. It is a type of medicine called a sclerosing agent. This medicine is to be given only by or under the direct supervision of your doctor. This product is available in the following dosage forms: Solution.